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Danielle Church provides an easy-to-read guide discussing the facts about synthetic pain reliever tramadol. She also provides common-sense tips for safe use of this medication.

Tramadol hydrochloride (hcl) was developed by the German pharmaceutical house Grünenthal GmbH in the late 1970s, hydrocodone no prescription 32. It's a synthetic drug with analgesic actions similar to codeine and antidepressant properties similar to SSRI drugs like Prozac, tramadol pain medicine for dogs. As such, it relieves pain and elevates mood at the same time.

Although not an anti-inflammatory like ibuprofen, tramadol does have unique anti-inflammatory properties. It's usually prescribed for short or long-term moderate to moderately-severe pain. Marketed under the brand name Ultram in the US and trade name Tramacet in Canada, the medication also comes in generic form.

What Is Tramadol Used For?

In addition to its analgesic and mood-elevating qualities, tramadol may be especially effective for relief from nerve pain and diabetic neuropathy that's unresponsive to opiate drugs like morphine, hydrocodone no prescription 32, oxycodone and hydrocodone. It's also been used to treat restless leg syndrome, treatment-resistant depression, tramadol pain medicine for dogs, high blood pressure, fibromyalgia and migraine headaches.

Tramadol and acetaminophen taken together may be more effective for pain than either drug alone. The combination of the two can mean that lower doses of both medications are required.

How It Works

Tramadol causes a shift in the body's perception of pain. Pain may still be present, but there's less discomfort because the pain signal is significantly reduced. The mood-elevating component adds a mildly stimulating and euphoric aspect to the mix, while the anti-inflammatory property reduces swelling. The combined effect increases one's ability to function and helps patients to carry on with daily life, purchase tramadol with online prescription.

Side Effects

The most common side effects of tramadol are:

Dizziness
Constipation
Nausea
Headache
Drowsiness
Vomiting
Sweating

Drug Interactions

Do not take tramadol with carbamazepine (Tegretol, Equetro, Carbatrol); these drugs reduce the concentration of tramadol in the bloodstream by inactivating it. Avoid mixing tramadol with quinidine (Quinaglute, Quinidex); these medications can increase the concentration of tramadol in the body by as much as 50-60%.

Patients on tramadol hcl should not take MAO Inhibitors (Parnate, Nardil), SSRIs (Prozac, Zoloft), anti-psychotics (Haldol, Thorazine), or medications for nausea and vomiting. Combining any of these with tramadol can cause seizures.

Tramadol should not be taken with other opiate drugs, alcohol, hydrocodone no prescription 32, anesthetics, tranquilizers, muscle relaxers, or sleeping pills. Respiratory failure, tramadol pain medicine for dogs, coma, and death could result.

Tramadol Cautions

Seizures can result from large single oral doses of 700 mg or more. Tramadol can cause seizures in those with epilepsy or other seizure disorders, tramadol pain medicine for dogs, head injuries, hydrocodone no prescription 32, or metabolic disorders.

Tramadol should be avoided by anyone with a history of addiction to alcohol or drugs, kidney disease, cirrhosis or other liver diseases, stomach disorders, tramadol pain medicine for dogs, mental illness or suicidal tendencies, tramadal. Do not take Tramadol if you are a dialysis patient. Tramadol should not be taken by anyone under age 16, and daily doses of more than 30 mg are not recommended for anyone over 75.

Is Tramadol Addictive?

This drug can produce psychological and physical dependence similar to morphine, hydrocodone no prescription 32. As such, tramadol pain medicine for dogs, it's highly addictive, especially in conjunction with its antidepressant effect. To avoid withdrawal symptoms, patients are advised to strictly limit their usage to the frequency and duration prescribed by a doctor, tramadol pain medicine for dogs. For short-term pain, the usual treatment course is no longer than five days.

Withdrawal Effects

Although tramadol was considered minimally addictive when it was introduced, it's apparently more addictive than originally thought. The 2010 Physicians Desk Reference (PDR) contains several warnings to this effect.

Patients have experienced physical withdrawal symptoms like nervous tremors, tramadol pain medicine for dogs, palpitations, sweating, tramadol pain medicine for dogs, muscle contractions, headache, insomnia and sensations similar to electrical shock, tramadal. Psychological symptoms like anxiety, panic, depression, anguish, hydrocodone no prescription 32, mood swings, aggression and anger have also been reported.

The longer a patient has used tramadol hcl before withdrawing, the more severe the withdrawal syndrome can be. Long-term users with chronic pain have said that because the drug has both pain relieving and stimulating effects, it is one of the most difficult analgesics to stop taking.

Withdrawal symptoms can develop within 12-20 hours after the last dose. The withdrawal process is said to last longer and be more uncomfortable than withdrawing from opiate drugs like morphine.

Tramadol hcl should not be used to manage opiate addiction or to wean addicts from opiate dependency. Given that the drug's stimulating properties make it doubly addictive, using it to treat opiate addiction can only worsen an existing condition.

Due to the unpleasant nature of the withdrawal process, long-term tramadol users should be weaned from the drug gradually while under a doctor's care. Discontinuing the medication suddenly can result in seizures.

Dosage

The usual dose of tramadol is 50-100 mg every 4-6 hours with a maximum of 400 mg per day. Used as directed, the drug is generally effective for up to 24 hours. Users are advised not to exceed the recommended dosage; overdose can be fatal.

For moderate pain, tramadol comes in 50 mg oral tablets that dissolve in the mouth, tramadol pain medicine for dogs. For those with chronic, severe pain, the long-acting time-release tablet comes in 100, tramadol effectiveness, 200, and 300 mg formulations and can be taken once per day, tramadal.

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