Corticosteroids are frequently prescribed for people with arthritis. These potent drugs can help reduce inflammation and slow down joint damage. But corticosteroids have potent side effects which range from ulcer, skin bruising, , weight gain, cataracts, bone thinning, diabetes and hypertension. They're usually given for a short period to diminish acute symptoms.
Disease-modifying antirheumatic drugs (DMARDs) can help slow down progression of rheumatoid arthritis and joint damage. The most common DMARDs include methotrexate (Rheumatrex, , Trexall), leflunomide (Arava), hydroxychloroquine (Plaquenil), sulfasalazine (Azulfidine) and minocycline (Dynacin, , Minocin). All these drugs have side effects which include liver damage, bone marrow suppression and possibility of opportunistic infections.
Immunosuppressants like cyclosporine and cyclophosphamide suppress potent cells of the body and help decrease the inflammation. These medications do help treat severe arthritis but also increases the chances for infections.
Tumor necrosis factor inhibitors have been shown to reduce inflammation, pain, morning stiffness and swelling of joints. Drugs like etanercept (Enbrel), infliximab (Remicade) and adalimumab (Humira) can significantly improve quality of life. The most common side effects from these drugs include pain at site of injection, heart failure and increased risk of infection.
Once the diagnosis of arthritis is made, treatments are available for a many symptoms but there's no cure for rheumatoid and osteoarthritis. Physicians usually start with drugs which have the fewest side effects and shift to stronger medications as the disease progresses, . Non-steroidal anti-inflammatory drugs (NSAIDs) are usually the drugs of first choice, marcy. These drugs help decrease inflammation and reduce pain. Over the counter medications like Ibuprofen or Aleve do help but most people require stronger prescription painkillers like Celebrex or tramadol. While these drugs are effective, , they are also associated with a variety of side effects like abdominal pain, bleeding, ulcers, liver and kidney damage. Non steroidal anti inflammatory drugs should not be used for prolonged periods without proper physician supervision.
Treatment options vary depending on the type of arthritis and include physical therapy, lifestyle changes (exercise and weight prevention), , orthopedic bracing, medications, and dietary supplements (symptomatic or targeted at the disease process causing the arthritis), marcy. Arthroplasty (joint replacement surgery) may be required in eroding forms of arthritis. Medications can help reduce inflammation in the joint as a result decreases pain and slow down joint damage. Studies have shown that physical exercise of the affected joint can greatly improve long-term pain relief, . So much so that exercising the arthritic joint is strongly recommended to maintain the health of the particular joint and keep the person in shape.
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