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Ralivia (tramadol HCl) is an extended-release oral tablet that slowly releases tramadol (an opioid analgesic) over a 24-hour period to manage continuous pain that is expected to persist for several days or more.

Ralivia (tramadol hydrochloride) is indicated for the management of pain of moderate severity in adults who require continuous treatment for several days or more. Ralivia (Tramadol HCl) is the brand name for once-daily extended-release tablets of a medication called tramadol. Ralivia (Tramadol HCl) belongs to a class of pain medications known as opioids. Unlike other opioids, it also changes the level of two chemicals in the brain: norepinephrine and serotonin. Changes in the amounts of these two chemicals can also provide pain relief, long does tramadol stay your system. Ralivia (Tramadol HCl) is different from other pain medications. It has no association with heart disease or stomach ulcers.

Do not take Ralivia (Tramadol HCl) if:

1. your doctor did not prescribe it for you
2. you are allergic to tramadol, opioids or any other ingredient in the tablets
3. you are consuming large amounts of alcohol or taking excessive amounts of other drugs that can depress respiration/breathing and consciousness
4. you are taking, or have taken within the past three weeks,

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, a monoamine oxidase inhibitor medication (e.g., Nardil®, Parnate®)
5. you have kidney or liver disease

Ralivia (Tramadol HCl) should not be used for minor pain that can be relieved by available (over-the-counter) pain killers, hydrocodone interactions.

Children under 18 years of age should not take Ralivia (Tramadol HCl) tablets.

Use of Ralivia (Tramadol HCl) tablets in pregnant women is not recommended.

If you have had seizures (convulsions) or have a condition that may put you at increased risk of seizures (epilepsy,

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head injury, metabolic disorders, alcohol or drug withdrawal),

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,
taking monoamine oxidase inhibitors,

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infection of the central nervous system (brain and spine), or are taking antidepressant medication, do not take Ralivia (Tramadol HCl) before discussing your history with your doctor.

Remember that Ralivia (Tramadol HCl) may be habit forming. Tell your doctor and pharmacist if you have a history of substance abuse or addiction.

Medicinal ingredient of Ralivia Extended Release Tablets:
Tramadol hydrochloride

Unsafe Raliva & Tramadol interactions:

Drugs that may interact with RALIVIA include:

alcohol or other sedative drugs may enhance the drowsiness caused by tramadol;
carbamazepine (Tegretol®) may increase the metabolism of tramadol and reduce the analgesic effect
tricyclic antidepressants, selective serotonin re-uptake inhibitors (SSRIs),

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,
antipsychotics used concomitantly can lower the seizure threshold
protease inhibitors (e.g.,

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,
ritonavir) co-administration may increase the blood levels of tramadol
- digoxin (Lanoxin®), warfarin or warfarin-like medications -rare reports of toxicity have been reported when taken with tramadol

Symptoms or Signs of Ralivia/Tramadol Overdose:

The most important sign of overdose is decreased breathing (abnormally slow or weak breathing), or extreme drowsiness. If you accidentally take an overdose of RALIVIA, contact your doctor and/or the nearest hospital and/or Emergency Room and/or Poison Control Centre immediately, even though you may not feel sick.

Raliva (Tramadol) Side Effects include dizziness, nausea,

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,
constipation and headache.



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