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Zydol capsules, soluble tablets and injection all contain the active ingredient tramadol hydrochloride, which is a type of medicine called an opioid painkiller. (NB. Tramadol is also available without a brand name, ie as the generic medicine.)

Opioid painkillers work by mimicking the action of naturally occurring pain-reducing chemicals called endorphins. Endorphins are found in the brain and spinal cord and reduce pain by combining with opioid receptors, by cod tramadol.

Tramadol mimicks the action of our natural endorphins by combining with the opioid receptors in the brain and spinal cord. This blocks the transmission of pain signals sent by the nerves to the brain. Therefore, sniffing tramadol effects, even though the cause of the pain may remain, less pain is actually felt.

Tramadol also works by enhancing the activity of neurotransmitters in the brain and spinal cord. Neurotransmitters are chemical compounds that act as chemical messengers between the nerve cells. Tramadol enhances the effect of the neurotransmitters serotonin and noradrenaline, by cod tramadol, and this action also helps relieve pain, tramadol gout.

Tramadol is a fairly strong painkiller that is used in the management of moderate to severe pain, by cod tramadol. It is given by injection when administration by mouth is not possible, for example for pain following surgery, by cod tramadol. The injection is given into a muscle or vein, or via a drip into a vein (intravenous infusion).

Zydol capsules and soluble tablets are taken by mouth up to six times a day, depending on the severity of the pain. Zydol soluble tablets should be dissolved in at least 50ml of water before taking. These forms of tramadol should not be taken more often than every four hours and you should not exceed the dose prescribed by your doctor.

For more prolonged pain relief, by cod tramadol, modified release forms of tramadol that can be taken once or twice a day are available, tramadol gout. See the products linked at the end of this factsheet for more information.

What is it used for?
Moderate to severe pain.

Warning!

This medicine may cause drowsiness. If affected do not drive or operate machinery. Alcohol should be avoided.

Some people may rarely experience withdrawal symptoms when they stop taking this medicine. These may include feeling agitated, anxious, by cod tramadol, nervous or shaky, extended release tramadol abuse of, or having difficulty sleeping. Tell your doctor if you experience any of these symptoms after stopping this medicine. These effects usually disappear after a few days.

This medicine is not recommended for children under 12 years of age.

This medicine is not recommended for people with severely decreased kidney function.

Use with caution in

Elderly people

Decreased kidney function

Decreased liver function

Asthma

Slow, shallow breathing (respiratory depression)

History of drug dependence or abuse

Head injury

Increased pressure in the brain (raised intracranial pressure)

Reduced blood flow to vital internal organs (shock)

History of convulsions, eg epilepsy.

Not to be used in

People under the influence of (intoxicated with) alcohol, sleeping tablets, tranquilizers, psychotropic drugs (those affecting mood or emotions) or other painkillers that act on the brain, sniffing tramadol effects, eg morphine, codeine

People who have taken a monoamine-oxidase inhibitor antidepressant (MAOI) in the last 14 days

Pregnancy

Breastfeeding

Uncontrolled epilepsy.

This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.

If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.

Pregnancy and Breastfeeding

Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby, tramadol gout. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.



The safety of this medicine during pregnancy has not been established. It may be harmful to a developing baby and could cause withdrawal symptoms in a newborn baby if used during the third trimester. The manufacturer therefore states that this medicine should not be used during pregnancy, sniffing tramadol effects. Seek medical advice from your doctor.

This medicine passes into breast milk in small amounts, by cod tramadol. The manufacturer recommends that women who are breastfeeding should not use this medicine. Seek medical advice from your doctor.

Label warnings

This medication may cause drowsiness. If affected do not drive or operate machinery. Avoid alcoholic drink.

Side effects

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.



Disturbances of the gut such as diarrhoea, constipation, nausea, vomiting or abdominal pain

Dizziness

Drowsiness

Headache

Sweating

Awareness of your heartbeat (palpitations)

Increased heart rate (tachycardia)

A drop in blood pressure that occurs when going from lying down to sitting or standing, which results in dizziness and lightheadedness (postural hypotension)

Skin reactions such as rash and itch

Blurred vision

Dry mouth

False perceptions of things that are not really there (hallucinations)

Nightmares

Confusion

Changes in mood

Slow, extended release tramadol abuse of, shallow breathing (respiratory depression)

Muscle weakness

Difficulty passing urine

The side effects listed above may not include all of the side effects reported by the drug's manufacturer.

For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

How can this medicine affect other medicines?

It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, by cod tramadol, check with your doctor or pharmacist before taking any new medicines while taking this one, to ensure that the combination is safe, by cod tramadol.

The manufacturer states that this medicine should not be taken at the same time as, or within two weeks of, MAOI antidepressants such as phenelzine or tranylcypromine.

There may be an increased risk of convulsions or seizures if tramadol is taken with the following medicines:



antipsychotic medicines

bupropion

mefloquine

SSRI antidepressants (eg fluoxetine)

tricyclic antidepressants (eg amitriptyline).

If tramadol is taken with SSRI antidepressants such as fluoxetine, or triptans for migraine such as sumatriptan, there may also be an increased risk of other side effects, as all these medicines enhance the activity of serotonin in the brain.

There may be an increased risk of drowsiness and sedation if tramadol is taken with any of the following (which can also cause drowsiness): by cod tramadol,



alcohol

antipsychotics, eg haloperidol

barbiturates, eg phenobarbital, amobarbital

benzodiazepines, eg diazepam, temazepam

other opioids, eg morphine, codeine

sedating antihistamines, eg chlorphenamine, hydroxyzine

sleeping tablets, eg zopiclone

tricyclic antidepressants, eg amitriptyline.

Carbamazepine may decrease the blood level of tramadol, which may make it less effective at relieving pain.

Tramadol may enhance the anti-blood-clotting effect of anticoagulant medicines such as warfarin. If you are taking warfarin your blood clotting time (INR) should be monitored when you start and stop treatment with tramadol.

Other medicines containing the same active ingredient Dromadol SR Larapam SR Mabron Tramake Tramake Insts Zamadol Zamadol SR Zamadol 24hr Zydol SR Zydol XL

Tramadol capsules and injection are also available without a brand name, ie as the generic medicine.






Generic Name: Tramadol Tablets (TRA-ma-dole)
Brand Name: Ultram

Tramadol hydrochloride tablets helps relieve different types of pain, by cod tramadol. Tramadol is the Generic form of Ultram. ULTRAN ® (tranadol hydrochloride tablets) is a prescription medication indicated for the management of moderate to moderately severe pain.

ULTRAM received U.S. Food and Drug Administration (FDA) approval in March, by cod tramadol, 1995. Tramadol has been prescribed to more than 55 million patients worldwide and ULTRAM has been prescribed to more than 21 million patients in the United States alone.

Tramadol is used for:

Treating moderate to moderately severe pain.
Tramadol is an analgesic. It works in certain areas of the brain and nervous system to decrease pain.

Do NOT use Tramadol if:

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; you are allergic to any ingredient in Tramadol

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;
you have severe diarrhea due to taking an antibiotic

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;
you are intoxicated with alcohol, other opioids or narcotics (eg, morphine, codeine), tramadol gout, sedatives or sleeping medicines (eg, temazepam, tramadol and risperdol, zolpidem), or other medicines
• you are taking nefazodone, by cod tramadol, carbamazepine, or sodium oxybate (GHB)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Tramadol:

Some medical conditions may interact with Tramadol. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

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; if you are pregnant, tramadol gout, planning to become pregnant, or are breast-feeding

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;
if you are taking any prescription (especially depression medicines) or nonprescription medicine, herbal preparation, sniffing tramadol effects, or dietary supplement
• if you have allergies to medicines, foods, by cod tramadol, or other substances
• if you are allergic to codeine, by cod tramadol, a codeine-related medicine (eg, hydrocodone, dihydrocodeine, oxycodone), morphine, or a morphine-related medicine (eg, hydromorphone)
• if you have a history of alcohol abuse, substance abuse, prince soma asman gadal, or suicidal thoughts or behaviors
• if you have or recently have had any head injury, brain injury or tumor, increased pressure in the brain, tramadol and risperdol, or infection of the brain or nervous system
• if you have a history of stomach or intestinal problems, sniffing tramadol effects, asthma or other lung or breathing problems, by cod tramadol, epilepsy, seizures, or chronic inflammation or ulceration of the bowels

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;
if you have had recent abdominal surgery
• if you have heart problems, liver problems (eg, hepatitis), kidney problems, thyroid problems, enlargement of the prostate gland, or urinary problems

This may not be a complete list of all interactions that may occur. Ask your health care provider if Tramadol may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Tramadol:

Use Tramadol as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Tramadol by mouth with or without food.

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; If you miss a dose of Tramadol , by cod tramadol, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule, extended release tramadol abuse of. Do not take 2 doses at once.

Ask your health care provider any questions that you may have about how to use Tramadol.

Important Safety Information:

• Tramadol may cause drowsiness and dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Tramadol with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

• Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Tramadol ; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.

• Tramadol may cause dizziness; alcohol, hot weather, exercise, or fever may increase this effect. To prevent it, sit up or stand slowly, by cod tramadol, especially in the morning, sniffing tramadol effects. Sit or lie down at the first sign of this effect.

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; Tell your doctor or dentist that you take Tramadol before you receive any medical or dental care, emergency care, by cod tramadol, or surgery.

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; Use Tramadol with caution in the ELDERLY; they may be more sensitive to its effects.

• Tramadol should not be used in CHILDREN younger than 16 years old;

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; safety and effectiveness in these children have not been confirmed.

• PREGNANCY and BREAST-FEEDING: Tramadol has been shown to cause harm to the fetus. If you think you may be pregnant, by cod tramadol, contact your doctor, extended release tramadol abuse of. You will need to discuss the benefits and risks of using Tramadol while you are pregnant. Tramadol is found in breast milk, prince soma asman gadal. Do not breast-feed while taking Tramadol.

When used for long periods of time or at high doses, Tramadol may not work as well and may require higher doses to obtain the same effect as when originally taken, tramadol gout. This is known as TOLERANCE. Talk with your doctor if Tramadol stops working well. Do not take more than prescribed.

Some people who use Tramadol for a long time without a break may develop a physical need to continue taking it. This is known as physical DEPENDENCE. If you suddenly stop taking Tramadol , you may experience WITHDRAWAL symptoms including anxiety; diarrhea;

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; fever, runny nose, or sneezing; goose bumps and abnormal skin sensations; nausea; vomiting; pain;

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;
rigid muscles;

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;
rapid heartbeat;

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;
seeing, hearing or feeling things that are not there; shivering or tremors; sweating; and trouble sleeping.

Possible side effects of Tramadol:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation;

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; diarrhea; dizziness; drowsiness; increased sweating;

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;
loss of appetite;

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;
nausea.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing;

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;
tightness in the chest; swelling of the mouth, face, lips, or tongue); agitation; fainting; fever;

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;
incoordination; muscle stiffness or tremor; seizures.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider.

Proper storage of Tramadol:

Store Tramadol at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, by cod tramadol, and light. Do not store in the bathroom. Keep Tramadol out of the reach of children and away from pets.

General Information:

• If you have any questions about Tramadol , please talk with your doctor, extended release tramadol abuse of, pharmacist, or other health care provider.
• Tramadol is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Tramadol. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, by cod tramadol, or other health care provider.

This information is a summary only. It does not contain all information about Tramadol. If you have questions about the medicine you are taking or would like more information, tramadol gout, check with your doctor, pharmacist, or other health care provider.




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