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Disease-modifying antirheumatic drugs (DMARDs) can help slow down progression of rheumatoid arthritis and joint damage. The most common DMARDs include methotrexate (Rheumatrex, Trexall), leflunomide (Arava), hydroxychloroquine (Plaquenil), , sulfasalazine (Azulfidine) and minocycline (Dynacin, postan forte and tramadol, Minocin), . All these drugs have side effects which include liver damage, bone marrow suppression and possibility of opportunistic infections.
Immunosuppressants like cyclosporine and cyclophosphamide suppress potent cells of the body and help decrease the inflammation, . These medications do help treat severe arthritis but also increases the chances for infections.
Tumor necrosis factor inhibitors have been shown to reduce inflammation, postan forte and tramadol, pain, morning stiffness and swelling of joints. Drugs like etanercept (Enbrel), infliximab (Remicade) and adalimumab (Humira) can significantly improve quality of life. The most common side effects from these drugs include pain at site of injection, heart failure and increased risk of infection.
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Treatment options vary depending on the type of arthritis and include physical therapy, lifestyle changes (exercise and weight prevention), orthopedic bracing, , medications, and dietary supplements (symptomatic or targeted at the disease process causing the arthritis), . Arthroplasty (joint replacement surgery) may be required in eroding forms of arthritis, postan forte and tramadol. Medications can help reduce inflammation in the joint as a result decreases pain and slow down joint damage, . Studies have shown that physical exercise of the affected joint can greatly improve long-term pain relief, postan forte and tramadol. So much so that exercising the arthritic joint is strongly recommended to maintain the health of the particular joint and keep the person in shape.
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