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Tramadol is the generic form of Ultram,

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. This medication is an analgesic that is used to treat or prevent pain. Tramadol's molecular weight is 299.8. Tramadol hydrochloride is a white,

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,
non-sweet, scentless and crystalline powder. This can be easily soluble in both water and ethanol with a pKa of . The n-octanol water coefficient, logP is at a pH of 7. ULTRAM pills are white and have 50 mg of Tramadol hydrochloride,

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. Here are the inactive ingredients: wax, corn starch,

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,
titanium dioxide, hypromellose, sodium starch glycolate, lactose,

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,
polysorbate 80, magnesium stearate,

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,
polyethylene glycol,

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,
microcrystalline cellulose.

Drug Interactions

Studies have revealed that Tramadol (Ultram) is not likely to inhibit the CYP3A4-mediated metabolism of other medications when Tramadol tablets is given concurrently at therapeutic doses. Since observed maximal plasma concentrations after multiple oral doses are higher than expected based on single-dose data, it does not appear that Tramadol (Ultram) induces its own metabolism in humans. As measured using animal subjects,

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, Tramadol is a mild inducer of some drug metabolism.

Tramadol Storage

Tramadol should be stored at 25 degrees Celsius (77 degrees Fahrenheit); there are exceptions in the range of 15-30 degrees Celsius (59-86 degrees Fahrenheit).

Use With Carbamazepine

The analgesic effect of ULTRAM may be drastically reduced in those who also take carbamazepine. It is not a good idea to take Ultram and carbamazepine together because Tramadol's metabolism is increased by carbamazepine, and seizure can result.

Use With Quinidine

Tramadol tablets is metabolized to M1 by CyP2D6. Quinidine selectively inhibits that isoenzyme. For this reason, concomitant administration of quinidine and ULTRAM causes an increase in concentrations of Tramadol (Ultram) and a reduction in concentrations of M1,

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. Today clinical consequences of these findings are not known. It has been shown via in vitro drug interaction studies in human liver microsomes that Tramadol tablets does not affect the metabolism of quinidine.

Use With Inhibitors of CYP2D6

It has been shown that the metabolism of Tramadol (Ultram) could be somewhat inhibited when inhibitors of CYP2D6 such as fluoxetine, paroxetine, and amitriptyline are taken concurrently.

Use With Cimetidine

Utilizing ULTRAM concurrently with cimetidine does not cause clinically significant changes in Tramadol Tablets pharmacokinetics. Therefore,

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, there are no changes of the ULTRAM dosage suggested.

Use With MAO Inhibitors

There have been some reports of interactions with MAO Inhibitors as a result of interference with detoxification mechanisms for some centrally acting drugs (see WARNINGS, Use With MAO Inhibitors).

Use With Digoxin and Warfarin

Since this drug has come to market, it has been found that on rare occasions, it results in Digoxin toxicity and alteration in the effect of Warfarin, including elevation of prothrombin times.

Children

Information regarding the effects of Tramadol (Ultram) is limited to patients older than 16 years of age.

Precautions for Using Tramadol

It is critical to be aware that Tramadol is a narcotic and,

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, like all narcotics, can be habit forming. It is crucial to use this drug as your doctor has prescribed it,

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,
and only as your doctor has prescribed it. Don't consume a larger amount than the dosage that is recommended. If you have health problems like liver or kidney disease, be sure to inform your physician. Due to the possibility of Tramadol causing drowsiness, you should not drive until you know how it may affect you,

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. When taking Tramadol, you must never drink alcohol. Let your physician know what else you are taking,

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,
both prescription and herbal remedies, like St. John's Wort.

Chronic pain is well treated by taking Tramadol Tablets. Some side effects can occur, including nervousness,

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, sweating, chills, dry mouth, dizziness, itching, rashes, changes in mood,

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heartburn, constipation, headache, sleepiness, etc., but normally these symptoms are not severe enough to remove a person from the medication.

If you have been thinking about taking Tramadol or your doctor has already written a prescription, then take care to follow their instructions exactly.





When it comes to body pain, one of the best ways of dealing with it is to find an effective relief that can provide you with instant results. Tramadol,

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, a popular painkiller,

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mostly resorted to by patients who experience moderate to severe pain. So what is tramadol? This is actually a synthetic agent as 4-phenyl-piperidine analogue of codeine,

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. This particular drug is also known to act like a morphine.

For tramadol to help you get rid of the pain, it works by thwarting the brainís receptors which are responsible for conveying the message of pain in the body,

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. It is safe to take this medicine once it is taken for short durations of time and under the doctorís guidance. Many medical professionals suggest that this medicine should only be taken during emergency situations and for moderate to severe pain only.

Since Tramadol is an effective pain reliever, many pharmaceutical companies already offered different brands for this drug in the market. Some popular brands are Ultram, Ultracet,

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, Ryzolt, Tramal, and Tramacet. You can purchase the drug in its regular form or in extended time release capsules. These are available in 50 mg intended for moderate pain. Higher dosage is also available from 100 mg, 200 mg up to 300 mg. Higher dosages are only prescribed for severe pain and for other serious illnesses where immediate pain management is required.

Another thing to remember when on tramadol medication is that it is recommended that you take the medicine in the same form as prescribed by your doctor,

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. Tramadol should be taken as a whole,

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. You will not get addictive to the medicine once it is taken for only short durations. Once the medicine is used for longer periods then it will commonly result to dependence and resistance to the drug,

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. So instead of easing the pain at lower dosages, you will later increase the intake of this drug to feel its effects. Symptoms of overdose may include cold and clammy skin, low body temperature, slowed breathing and heartbeat, drowsiness, lightheadedness, seizures, deep sleep and loss of consciousness.

Once you notice that you have difficulty in breathing or tightness of the chest, swelling of eyelids, face or lips, develop rash or hives, then it is high time that you tell your doctor about it the soonest possible time,

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. It is also important that you avoid alcohol when taking tramadol. Meanwhile,

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,
women who are planning on becoming pregnant must consult it first with a doctor so he can discuss the benefits and risks of using tramadol during pregnancy. Tramadol is excreted in breast milk so it is only logical for women to avoid breastfeeding while taking tramadol,

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.

The dosage of tramadol or any change in the prescription should only be done after consulting with your doctor. If you notice any unpleasant side effects caused by this drug, then you need to talk to your doctor about it,

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. It is better to be honest about any adverse reactions of your present medication so that immediate remedy can be provided,

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Tramadol can also be taken in combination with Carbamazepine and it is normally prescribed for the treatment of epilepsy and bipolar disorder. Carbamazepine also lessens the effect of tramadol. However, you should be careful about drug interactions as it can lead to unwanted side effects or prevent the medicine in easing your pain,

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. When this happens, you need to consult a health care professional if you have questions on drug interactions with tramadol.

Aside from pain management, tramadol can also be used for people who have chronic pain disorders or for patients who just had dental surgery,

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. Tramadol can also help alleviate the pain brought by migraine, sprains, broken ligaments, chronic pain, severe back pain,

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cancer pain and a whole lot more. With all these information,

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you will definitely have an idea on what tramadol is and what it can do to your body.




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