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seizure (convulsions)
a red, blistering, peeling skin rash; or
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This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. What other drugs affect Tramadol? You may be more likely to have a seizure (convulsions) if you take tramadol while you are using certain other medicines. Do not take tramadol without telling your doctor if you also use any of the following medications:
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Cold or allergy medicine, sleeping pills, tramadol worldwide, muscle relaxers, , and medicine for seizures or anxiety can add to sleepiness caused by tramadol, tramadol worldwide. Tell your doctor if you regularly use any of these medicines, or any other pain medication. Tell your doctor about all other medicines you use, especially:
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warfarin (Coumadin)
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ketoconazole (Extina, Ketozole, Nizoral, tramadol worldwide, Xolegal)
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St. John's wort
quinidine (Quin-G); or
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Keep the tablet in its blister pack until you are ready to take it
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Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing
Swallow several times as the tablet dissolves. If desired, you may drink liquid to help swallow the dissolved tablet
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sedatives or tranquilizers (such as Valium)
medicine for depression or anxiety
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Seizures have occurred in some people taking tramadol, tramadol desipramine. Your risk of a seizure may be higher if you have any of these conditions:
a history of drug or alcohol addiction
a history of epilepsy or other seizure disorder
a history of head injury
a metabolic disorder; or
if you are also taking an antidepressant, muscle relaxer, or medicine for nausea and vomiting
Talk with your doctor about your individual risk of having a seizure while taking tramadol. If you have any of these other conditions, , you may need a tramadol dose adjustment or special tests:
kidney disease (or if you are on dialysis)
cirrhosis or other liver disease
a stomach disorder; or
a history of depression, mental illness, or thoughts of suicide
FDA pregnancy category C. It is not known whether tramadol will harm an unborn baby. Tramadol may cause serious or fatal side effects in a newborn if the mother uses the medication during pregnancy or labor. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Tramadol can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give this medication to anyone younger than 18 years old without the advice of a doctor. What warnings do you have for Tramadol? The following warnings are available for this medication:
Do not chew or crush.
Do not drink alcohol.
Check with your doctor before becoming pregnant.
May cause drowsiness.
May impair driving.
Obtain advice for OTCs.
Where can I get more information regarding Tramadol? Your pharmacist can provide more information about tramadol.
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